What Causes Brain Fog?

What Causes Brain Fog

Whether it’s a grandchild turned math teacher, a spouse turned verbal punching bag, or a neighbor’s name turned tongue twister, there’s no doubt brain fog takes a deep toll on our relationships.

Brain fog patients report being baffled by their own mood swings and behaviors. Why the nagging fatigue, sudden irritability, and draining anxiety? Why the numbing depression, disabling headaches, and maddening insomnia?

They’re frustrated, frightened, and anxious to understand why they can no longer remember words or information, organize thoughts, problem-solve in routine situations, focus on a task or chat, plan their day (or even their dinner), and sometimes, recognize common shapes.

These patients are baffled by their brain fog.

The root causes of their symptoms may lie in:

  • A brain chemistry imbalance
  • A mild brain injury
  • Inflammation
  • Nutrient deficiency

Whatever the cause, recent studies have shown that Cerenx may help nutritionally manage your brain fog.

For years, international research teams have been sourcing, synthesizing, and clinically validating this brain-fog-alleviating medical food product, which may help resolve brain fog symptoms.

To learn more and discover how Cerenx® can improve your mental health, call (800) 971-3721 (ext 3) or contact us here.

Brain Chemistry Imbalance

These unnerving cognitive and emotional changes are often stimulated by menopause (the gradual loss of estrogen in women) and andropause (the gradual loss of testosterone in men).

More than 2 million women reach menopause every year,1 and about 25 million American men have experienced andropause2 in this century. Menopause and andropause symptoms include:

  • Low energy and decreased motivation
  • Depression
  • Insomnia
  • Mental fog and difficulty concentrating

Estrogen and testosterone help regulate the stress hormone cortisol. Low levels of these hormones affect neurotransmitters in our brain, causing our blood circulation and energy metabolism to slow down.

An over- or under-production of thyroid hormones—which regulate body temperature, metabolism, and heart rate—can also stimulate brain fog.3 Imbalances of these hormones can induce depression and anxiety, which further degrade brain function.

The phospholipids in our brain cells mediate the activity of these hormones, as well as form membrane barriers that protect us from charged particles. When these phospholipids begin to degrade, so does our brain’s information processing ability.

The more phospholipids our brain can produce, the more effectively it can function and mediate our hormones. Research suggests Citicoline stimulates the production of membrane phospholipids in brain cells, while simultaneously reducing the degradation of those phospholipids.

In clinical trials patients who took Citicoline experienced significant improvement in cognitive status during follow up as compared to their placebo-taking counterparts. And the cognitive status of the Citicoline-taking patients was still improving a year later.4

Unaddressed brain fog can profoundly impact your professional, social, and personal life. To feel the relief these study subjects experienced for yourself, try Cerenx®.

To learn more and discover how Cerenx® can improve your mental health, call (800) 971-3721 (ext 3) or contact us here.

Mild Brain Injury

Mild Brain Injury

This term is deceiving. Mild brain injury—caused by a significant force to the head or upper body that shakes the brain inside the skull—may not feel so harmful upon impact. A post-injury MRI or CT scan may not even detect anything “abnormal.” Yet the resulting brain damage can be life-altering. MBIs can induce changes in mental status such as:

  • amnesia or disorientation
  • mental fogginess or confusion
  • nausea/vomiting
  • blurred vision
  • headache
  • balance deficits/dizziness
  • anxiety/impulsivity
  • loss of consciousness

The MBI recovery process is uneven. One day you may feel 100% better, and the next, you may feel the same as you did right after the injury. So, brain health maintenance is crucial.

According to the Centers for Disease Control (CDC), high school athletes suffer about 300,000 MBIs (or concussions) every year.

Studies show that their health and performance later in life can be seriously affected if the root cause of injury is not treated.5

Phospholipids are involved in many of the brain cell functions that are damaged by concussions. A study published in the Journal of Attention Disorders showed that adolescent males who took Citicoline, the active ingredient in Cerenx®, saw improved motor function on the Finger Tap Test and the Ruff 2&7 Speed task.6

Don’t wait until your teenager’s concussion comes back to haunt him or her in adulthood – discover how Cerenx® help maintain brain health by calling (800) 971-3721 (ext 3) or contact us here

Other potential causes of brain fog


Inflammation can stimulate brain fog in many common conditions that are often difficult to diagnose. These include:

Leaky gut Syndrome

In patients with leaky gut syndrome, inflammation causes chemicals to travel from the intestine through the blood and to the brain, transferring that inflammation.7

Multiple Sclerosis

MS-caused inflammation can inflict lesions on the brain that affect information processing, memory, and executive functioning abilities. Many people living with MS will experience some changes in their memory and decision-making ability.8

Inflammation affects so many of our systems and organs – don’t let it disrupt your brain function too. To delve further into the clinically-validated promising results of Cerenx® call (800) 971-3721 (ext 3) or contact us here.

Nutrient Imbalance

Many brain fog patients are experiencing what neurologists call brain malnourishment. Not getting enough crucial nutrients in our diet can degenerate many of our brain functions.

Some common culprits include:

Magnesium deficiency

Magnesium supports brain plasticity—the ability to remodel connections between brain cells—which is the physical foundation of memory and optimal learning. Studies suggest that brain magnesium levels are low among people with treatment-resistant depression.9

Vitamin B12 deficiency

Vitamin B12 (or cobalamin) is an essential vitamin that enables function and development of brain and nerve cells by maintaining the sheaths that protect our nerves and their impulse transmission. Vitamin B12 helps synthesize and maintain myelin, the fatty substance which forms these sheaths. Vitamin B12 deficiency damages that myelin sheath and can cause severe neurological problems.10

Glucose imbalance

The high glucose levels of diabetes patients can damage blood vessels and white matter (where nerves talk to each other) in the brain, causing cognitive impairment that neurologists call vascular dementia.11

Amino acid deficiency

Indispensable amino acids like tryptophan, tyrosine, histidine, and arginine are used by our brain to synthesize neurotransmitters that affect our mood and brain functions. These protein precursors must be obtained in our diet.12

That’s why we’ve gone beyond supplements – Cerenx® is a medical food product for your brain.

Years or even decades of nutrient deficiencies can disrupt the neurotransmitters responsible for healthy brain function. It may be time to replenish and maintain them. To learn more about the clinical efficacy of Cerenx® click here.

Cerenx™ and Brain Fog?

Cerenx and Brain Fog

Decades of worldwide research on the efficacy of Citicoline – the active ingredient in Cerenx – shows promise for patients battling brain fog.

Depression and decreased motivation are believed to be stimulated by imbalances of the neurotransmitter dopamine. Multiple studies suggest Citicoline may have a triple effect on dopamine in the brain by:

– Increasing dopamine levels13

– Increasing density of dopamine receptors14

– Protecting dopamine-related neurons15

Lack of focus and waning verbal memory are commonly-reported brain fog symptoms in menopausal and andropausal patients. Recent clinical studies performed by MIT researchers and others demonstrated that taking Citicoline, the active ingredient in Cerenx, improved:

– Focus in healthy women16

– Verbal memory in aging adults17

What dose is needed to treat brain fog?

Stop wondering why foggy head frustrates and exhausts you so often. Whatever the exact cause, Cerenx may be able to help repair and restore your brain cells, your focus, and your memory.

Don’t neglect the maintenance of your most important organ. Nourish your brain to reduce the degradation of the phospholipids that maintain your neurotransmitters.

Most physicians will prescribe
that you take two
Cerenx® capsules (500 mg) daily.

Cerenx Bottle

Call (800) 971-3721 (ext 3) or click here to learn more and to discover how Cerenx can alleviate your brain fog.

Request More Information Today


https://www.acog.org/-/media/NewsRoom/MediaKit.pdf  http://www.menstuff.org/issues/byissue/andropause.html https://www.nahypothyroidism.org/clearing-the-air-about-thyroid-related-brain-fog/  4 Jose Alvarez-Sabín ,Estevo Santamarina, Olga Maisterra, Carlos Jacas ,Carlos Molina. Long-Term Treatment with Citicoline Prevents Cognitive Decline and Predicts a Better Quality of Life after First Ischemic Stroke. Int. J. Mol. Sci. 2016, 17, 390  5Amir Sariaslan, David J. Sharp,Brian M. D’Onofrio, Henrik Larsson, Seena Fazel. Long-Term Outcomes Associated with Traumatic Brain Injury in Childhood and Adolescence: A Nationwide Swedish Cohort Study of a Wide Range of Medical and Social Outcomes. Published: August 23, 2016. https://doi.org/10.1371/journal.pmed.1002103/  6 McGlade, E. et.al; The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males. Journal of Attention Disorders, 2015, 1-14. 7 Gareau MG. Microbiota-gut-brain axis and cognitive function. Adv Exp Med Biol. 2014;817:357-71.  https://www.nationalmssociety.org/Symptoms-Diagnosis/MS-Symptoms/Cognitive-Changes  9 Eby GA 3rd, Eby KL. Magnesium for treatment-resistant depression: a review and hypothesis. Med Hypotheses. 2010 Apr;74(4):649-60. doi: 10.1016/j.mehy.2009.10.051. Epub 2009 Nov 27.  10 Weir DG, & Scott JM (1999). Brain function in the elderly: role of vitamin B12 and folate. British medical bulletin, 55 (3), 669  11 Cynthia Fritschi, PhD RN and Laurie Quinn, PhD RN. Fatigue in Patients with Diabetes: A Review J Psychosom Res. 2010 Jul; 69(1): 33–41.  12 Harris R. Lieberman. Amino Acid and Protein Requirements: Cognitive Performance, Stress, and Brain Function. The National Academies Press.  13 Mahtab Roohi-Azizi, MSc, Somaye Arabzadeh, MD, Meysam Amidfar, MSc, Samrand Salimi, MD, Mohammad Reza Zarindast, PhD, Ali Talaei, MD, and Shahin Akhondzadeh, PhD. Citicoline Combination Therapy for Major DepressiveDisorder: A Randomized, Double-Blind,Placebo-Controlled Trial. Clinical Neuropharmacology • Volume 40, Number 1, January/February 2017 Citicoline Combination  14 Rosa Gimenez, josep Raich & Juan Aguilar Dept of Biochemistry, Faculty of Pharmacy, University of Barcelona. Br. J. Pharmacol, 104, 575-578 15 http://journals.sagepub.com/doi/abs/10.1177/1087054715593633D’Orlando KJ, Sandage BW Jr. Citicoline (CDPcholine): mechanisms of action and effects in ischemicbrain injury. Neurol Res 1995;17:281-284. 16 Mcglade, Erin & Locatelli, Allison & Hardy, Julia & Kamiya, Toshikazu & Morita, Masahiko & Morishita, Koji & Sugimura, Yoichiro & Yurgelun-Todd, Deborah. (2012). Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. Food and Nutrition Sciences. 03. 10.4236/fns.2012.36103. 17 Agnoli A, Bruno G, Fioravanti M. Therapeutic approach to senile memory impairment: a doubleblind clinical trial with CDP choline. eds. Alzheimer’s Disease:Proceedings of the Fifth Meeting of the International Study Group on the Pharmacology of Memory Disorders Associated with Aging. Boston, MA: Birkhauser;1989:649-654.

Brain Fog

Brain Fog

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